BIOMARKER REFERENCE

Hemoglobin A1c

Biomarker Reference Sheet — research tool, not FDA-cleared. Ranges under citation review.

Metadata

Code
HBA1C
Unit
%
Category
Metabolic Panel
Subcategory
Name (Russian)
Гликированный гемоглобин

Reference Ranges

Range typeValue
Male reference4–5.6 %
Female reference4–5.6 %
Optimal4.8–5.6 %

Sex-specific reference ranges from the registry. Generic reference_range column is not used.

Provenance

Source documentation pending — reference ranges are under citation review.

Interpretation

Low
Rare, may indicate hemolytic conditions
Optimal
Excellent long-term glucose control
High
Indicates chronic hyperglycemia

Used in Patterns

This biomarker contributes to the Insulin Resistance Detection model card.

Validation Snapshot

NHANES 2015–2016 distribution (N=5,992): n_valid 5,441 / 5,992; mean 5.82%, median 5.5%, p95 7.9%; 37.4% classified high (≥5.7%).

Age gradient: 18–39: 13.7% high; 60+: 60.2% high.

Source: Independent audit harness, NHANES 2015–2016 (commit c10afe8)

github.com/dimashibakov/zenlo-audit

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